| Skin |
| Feeling of warmth, flushing (erythema), itching, urticaria, angioedema, and "hair standing on end" (pilor erection) |
| Oral |
| Itching or tingling of lips, tongue, or palate |
| Edema of lips, tongue, uvula, metallic taste |
| Respiratory |
| Nose - Itching, congestion, rhinorrhea, and sneezing |
| Laryngeal - Itching and "tightness" in the throat, dysphonia, hoarseness, stridor |
| Lower airways - Shortness of breath (dyspnea), chest tightness, cough, wheezing, and cyanosis |
| Gastrointestinal |
| Nausea, abdominal pain, vomiting, diarrhea, and dysphagia (difficulty swallowing) |
| Cardiovascular |
| Feeling of faintness or dizziness; syncope, altered mental status, chest pain, palpitations, tachycardia, bradycardia or other dysrhythmia, hypotension, tunnel vision, difficulty hearing, urinary or fecal incontinence, and cardiac arrest |
| Neurologic |
| Anxiety, apprehension, sense of impending doom, seizures, headache and confusion; young children may have sudden behavioral changes (cling, cry, become irritable, cease to play) |
| Ocular |
| Periorbital itching, erythema and edema, tearing, and conjunctival erythema |
| Other |
| Uterine cramps in women and girls |
