| Features | AFRS | CRS with NP | CRS without NP |
| Bilateral nasal polyps | Yes (in most cases) | Yes - Required for diagnosis* | No - Exclusion of polyps is required for diagnosis |
| Allergic mucin | Yes - Required for diagnosis | May be present | May be present |
| Aspirin-associated respiratory disease | May be present | Asthma present in approximately 40% Aspirin intolerance and asthma present in approximately 15% | Rare |
| Evidence of IgE-mediated allergy to fungi | Yes - Required for diagnosis | May be present | May be present |
