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Structure and function of the SARS-CoV-2 spike protein

Structure and function of the SARS-CoV-2 spike protein
(A) The schematic structure of the spike (S) protein.
(B) The spike (S) protein binds to the receptor ACE2.
(C) The binding and virus-cell fusion process mediated by the spike (S) protein.
(D) The life cycle of SARS-CoV-2 in host cells.
SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.
Reprinted by permission from Macmillan Publishers Ltd: Acta Pharmacologica Sinica. Huang Y, Yang C, Xu XF, et al. Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19. Acta Pharmacol Sin 2020; 41:1141. Copyright © 2020. https://www.nature.com/aps/.
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