| VIM DBS | STN or GPi DBS | LCIG | CSAI | Pallidotomy | FUS thalamotomy | |
| Indications | Refractory PD tremor | Motor fluctuations or refractory PD tremor | Motor fluctuations | Motor fluctuations | Motor fluctuations | Refractory PD tremor |
| Can be performed bilaterally? | No | Yes | N/A | N/A | No | No |
| Surgery required? | Yes, scalp incision/burr hole | Yes, scalp incision/burr hole | Yes, PEG-J placement | No | Yes | No |
| Intentional brain lesion? | No | No | No | No | Yes | Yes |
| Reversible? | Yes | Yes | Yes | Yes | No | No |
| Randomized, placebo, or sham-controlled trial data available? | No | Yes | Yes | Yes | Randomized trial with blinded evaluators | Yes |
| Long-term data (>2 years) available? | Yes | Yes | Yes | Yes | Yes | Unknown |
| Clinical availability | Full | Full | Full | Not approved for use in United States | Full | Limited number of centers |
