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Glycemic control in type 2 diabetes

Glycemic control in type 2 diabetes
Glycemic control, estimated from the median hemoglobin A1C value, in patients with type 2 diabetes mellitus in the United Kingdom Prospective Diabetes Study (UKPDS) who were randomly assigned to receive intensive therapy with a sulfonylurea or insulin or to conventional treatment with diet; drugs were added if there were hyperglycemic symptoms or if the fasting blood glucose concentration was greater than 270 mg/dL (15 mmol/L). The A1C values were lower in the intensive therapy group but rose in both groups over time. The circles represent data for all patients, while the lines represent data for patients followed for 10 years.
A1C: HbA1c, glycated hemoglobin.
Data from: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352:837.
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