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Malignant epidural spinal cord compression: Scoring system to predict outcomes post-radiotherapy

Malignant epidural spinal cord compression: Scoring system to predict outcomes post-radiotherapy
Variable Post-RT ambulatory rate, percent Score
Type of primary tumor
Breast cancer 81 8
Prostate cancer 68 7
Myeloma/lymphoma 89 9
Non-small cell lung cancer 54 5
Small cell lung cancer 64 6
Cancer of unknown primary 45 5
Renal cell carcinoma 62 6
Colorectal cancer 64 6
Other tumors 59 6
Interval from tumor diagnosis to MSCC
≤15 months 58 6
>15 months 78 8
Visceral metastases at the time of RT
Yes 54 5
No 77 8
Motor function before RT
Ambulatory without aid 98 10
Ambulatory with aid 89 9
Not ambulatory 28 3
Paraplegic 7 1
Time of developing motor deficits before RT
1 to 7 days 37 4
8 to 14 days 69 7
>14 days 88 9
RT: radiotherapy; MSCC: metastatic spinal cord compression.
Reproduced with permission from: Rades D, Rudat V, Veninga T, et al. A score predicting posttreatment ambulatory status in patients irradiated for metastatic spinal cord compression. Int J Rad Oncol Biol Phys 2008; 72:905. Illustration used with the permission of Elsevier, Inc. All rights reserved.
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