| Cytochrome P450 isoenzymes involved in metabolism | |
| Busulfan | 3A4 |
| Cisplatin | 2E1, 3A4 |
| Cyclophosphamide | 2B6, 2C9, 3A4 |
| Cytarabine | 3A4 |
| Dacarbazine | 1A1, 1A2, 2E1 |
| Docetaxel | 1B1, 3A4, 3A5 |
| Doxorubicin | 2D6, 3A4 |
| Erlotinib | 1A1, 1A2, 3A4 |
| Etoposide | 1A2, 2E1, 3A4, 3A5 |
| Everolimus | 3A4 |
| Gefitinib | 3A4 |
| Hydroxyurea | Specific isoenzyme not reported |
| Idarubicin | 2D6, 2C9 |
| Ifosfamide | 2A6, 2B1, 2B6, 2C9, 2C18, 2C19, 3A4, 3A5 |
| Imatinib | 1A2, 2C9, 2C19, 2D6, 3A4 |
| Irinotecan | 3A4, 3A5 |
| Lapatinib | 2C8, 3A4 |
| Mitoxantrone | Specific isoenzyme not reported |
| Nilotinib | 3A4 |
| Paclitaxel | 2C8, 3A4, 3A5 |
| Procarbazine | 1A, 2B |
| Sorafenib | 3A4 |
| Sunitinib | 3A4 |
| Tamoxifen | 1A1, 1A2, 1B1, 2B6, 2C9, 2C19, 2D6, 2E1, 3A4, 3A5 |
| Temsirolimus | 3A4 |
| Teniposide | 3A4, 3A5 |
| Topotecan | 3A4 |
| Toremifene | 1A2, 3A4 |
| Tretinoin | 2C8, 2C9, 2E, 3A4 |
| Vinblastine | 3A4 |
| Vincristine | 3A4 |
| Vinorelbine | 3A4 |
