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UNOS criteria presence among patients withdrawn from life-sustaining treatment

UNOS criteria presence among patients withdrawn from life-sustaining treatment
Characteristics at time of withdrawal of life-sustaining treatments N (%)
n = 505 patients		 Percent with death ≤60 minutes Association with death ≤60 minutes
Relative risk* p-Value
UNOS criteria
Apnea 30 (6%) 77% 1.79 0.001
RR <8 (ie, RR 1 to 7) 12 (2%) 67% 1.50 0.13
RR <30 45 (9%) 29% 0.62 0.023
LVAD 2 (0.4%) 100% 2.22 0.12
RVAD 1 (0.2%) 100% 2.22 0.27
V-A ECMO 1 (0.2%) 0% 0.00 0.37
Pacemaker-unassisted heart rate <30 5 (1%) 80% 1.79 0.11
PEEP ≥10 and SaO2 ≤92% 50 (10%) 78% 1.89 0.001
FiO2 ≥0.5 and SaO2 ≤92% 94 (19%) 67% 1.68 0.001
V-V ECMO 5 (1%) 80% 1.79 0.11
Norepinephrine or phenylephrine ≥0.2 151 (30%) 70% 2.05 0.001
Dopamine ≥15 19 (4%) 79% 1.81 0.0024
IABP 1:1 or (dobutamine or dopamine ≥10 and CI ≤2.2) 25 (5%) 68% 1.55 0.018
IABP 1:1 and CI ≤1.5 1 (0.2%) 100% 2.22 0.27
Number of UNOS criteria present
0 249 (49%) 29% 1.00 0.001
1 146 (29%) 52% 1.83  
2 54 (11%) 65% 2.27  
3 39 (8%) 82% 2.88  
4 to 5 17 (3%) 76% 2.68  
UNOS: United Network for Organ Sharing; RR: respiratory rate; LVAD: left ventricular assist device; RVAD: right ventricular assist device; V-A ECMO: veno-arterial extracorporeal membrane oxygenator; PEEP: positive end-expiratory pressure; SaO2: oxygen saturation; FiO2: fraction of inspired oxygen; V-V ECMO: veno-venous extracorporeal membrane oxygenator; IABP: intra-aortic balloon pump; CI: cardiac index in liters/minute/meter2.
* Overall rate of death within 60 minutes for the entire sample of n = 505 patients is 45%.
From: DeVita MA, Brooks MM, Zawistowski C, et al. Donors after cardiac death: Validation of identification criteria (DVIC) study for predictors of rapid death. Am J Transplant 2008; 8(2):432-41. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1600-6143.2007.02087.x. Copyright © 2008 American Society of Transplantation and the American Society of Transplant Surgeons. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: permissions@wiley.com or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).
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