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Causes of small bowel bleeding

Causes of small bowel bleeding
Common causes Rare causes
Under age 40 years Over age 40 years Henoch-Schoenlein purpura
Inflammatory bowel disease NSAID ulcers Small bowel varices and/or portal hypertensive enteropathy
Meckel diverticulum Angioectasia Amyloidosis
Dieulafoy lesions Dieulafoy lesions Blue rubber bleb nevus syndrome
Neoplasia Neoplasia Pseudoxanthoma elasticum
Polyposis syndromes   Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)
    Kaposi sarcoma with AIDS
    Plummer-Vinson syndrome
    Ehlers-Danlos syndrome
    Inherited polyposis syndromes (FAP, Peutz-Jeghers)
    Malignant atrophic papulosis
    Hematobilia
    Aortoenteric fistula
    Hemosuccus entericus
FAP: familial adenomatous polyposis; NSAID: nonsteroidal anti-inflammatory drug.
Adapted by permission from Macmillan Publishers Ltd: American Journal of Gastroenterology. Gerson LB, Fidler JL, Cave DR, Leighton JA. ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding. Am J Gastroenterol 2015; 110:1265. Copyright © 2015. www.nature.com/ajg.
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